Lessee, operating leases, allowance for normal leasehold improvements.
Lessee Operating Leases Allowance For Normal Leasehold Improvements
Lessee, operating leases, allowance for normal leasehold improvements
Entity Address, City or Town
Entity Address, City or Town
Other Commitment, Total
Other Commitment
Increase in number of shares reserved for issuance, percent of common stock outstanding.
Increase In Number Of Shares Reserved For Issuance Percent Of Common Stock Outstanding
Increase in number of shares reserved for issuance, percent of common stock outstanding
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Reconciliation of U.S. Federal Statutory Income Tax Rate
Entity Ex Transition Period
Entity Ex Transition Period
Fair Value Disclosures [Abstract]
Accounting Standards Update and Change in Accounting Principle [Table]
Earnings Per Share [Abstract]
Fair Value, Inputs, Level 1 [Member]
Level 1
Domestic Tax Authority [Member]
Federal
Deferred revenue current and noncurrent.
Deferred Revenue Current And Noncurrent
Deferred revenue current and non-current
Stock Issued During Period, Value, New Issues
Issuance of common stock, net of issuance costs
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expense
Net Cash Provided by (Used in) Financing Activities [Abstract]
Financing activities
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend yield
Lessee, Operating Lease, Discount Rate
Clinical program
Clinical program
Clinical program | Segment
Issuance of common stock in connection with private placement, net of placement agent fees and offering costs, Amount
Issuance of common stock in connection with private placement, net of placement agent fees and offering costs, Amount
Amendment Flag
Amendment Flag
Capital Expenditures Incurred but Not yet Paid
Property and equipment purchases unpaid at end of period
Subsequent Event Type [Domain]
Subsequent Event Type
Research Development And Sales Arrangement Amount Received Upon Achievement Of Milestone
Research Development And Sales Arrangement Amount Received Upon Achievement Of Milestone
Lease Incentive, Payable, Current
Deferred lease incentive, current portion
Treasury Stock, Common [Member]
Treasury Stock
Share based compensation arrangement by share based payment award equity instruments other than options repurchased in period weighted average grant date fair value.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Repurchased In Period Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Repurchased
Operating Lease, Right-of-Use Asset
Operating lease right-of-use assets
Other Commitments [Axis]
Other Commitments
Earnings Per Share, Policy [Policy Text Block]
Net Income (Loss) Per Share
Statement [Table]
Statement [Table]
Operating Lease, Liability, Noncurrent
Operating lease liability, excluding current portion
Number of Operating Segments
Number of operating segment
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Deferred tax assets orphan drug credit carryforwards.
Deferred Tax Assets Orphan Drug Credit Carryforwards
Orphan drug credit carryforwards
Two thousand nineteen and two thousand sixteen stock incentive plan.
Two Thousand Nineteen And Two Thousand Sixteen Stock Incentive Plan [Member]
2019 Plan and 2016 Plan
Restructuring Charges, Total
Restructuring Charges
Restructuring Charges
Change in variable consideration constrained
Change In Variable Consideration Constrained
Change in variable consideration constrained.
Reimbursement Payment Recieved.
Reimbursement Payment Recieved
Reimbursement Payment Recieved
Common Stock, Capital Shares Reserved for Future Issuance
Shares reserved for future issuance
Shares reserved for future issuance under the 2022 Inducement Stock Incentive Plan
Series B Preferred Stock [Member]
Series B Convertible Preferred Stock
Auditor Firm ID
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Unvested, Ending balance
Weighted Average Grant Date Fair Value, Unvested, Beginning balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Vested
Temporary Equity, Par or Stated Value Per Share
Convertible preferred stock, share price
Increase (Decrease) in Deferred Revenue
Deferred revenue
Cash equivalents and marketable securities accumulated gross unrealized gains before tax.
Cash Equivalents And Marketable Securities Accumulated Gross Unrealized Gains Before Tax
Total cash equivalents and marketable securities, Gross Unrealized Gains
Deferred Tax Assets, Operating lease liability
Deferred Tax Assets, Operating lease liability
Operating lease liability
Stock issued during period shares initial public offering net of underwriting discounts, commissions and offering costs.
Stock Issued During Period Shares Initial Public Offering Net Of Underwriting Discounts Commissions And Offering Costs
Initial public offering net of underwriting discounts, commissions and offering costs, Shares
Income Tax Authority [Domain]
Income Tax Authority
Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures and Expirations in Period, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period
Number of Shares, Cancelled
Employee Stock [Member]
2019 Employee Stock Purchase Plan
Payment for Prepaid Research Funding.
Payment For Prepaid Research Funding
Payment for prepaid research funding
Costs Associated with Exit or Disposal Activity or Restructuring [Policy Text Block]
Restructuring Expenses
Employee-related Liabilities, Current, Total
Employee-related Liabilities, Current
Payroll and benefits
Lessee, Operating Leases [Text Block]
Leases
Share-Based Payment Arrangement, Option [Member]
Outstanding Stock Options
Stock Option
Liabilities and Equity
Total liabilities and stockholders’ equity
Schedule of accrued expenses and other current liabilities.
Schedule Of Accrued Expenses And Other Current Liabilities Table [Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Accounts Receivable, Related Parties
Plan Name [Domain]
Plan Name
Other Liabilities, Current, Total
Other Liabilities, Current
Other
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Vested
Aggregate intrinsic value of restricted stock awards vested
Unbilled Receivables, Current
Unbilled accounts receivable
Stock Issued During Period, Value, Employee Benefit Plan
Issuance of common stock under employee benefit plans
Stock Issued During Period, Shares, Employee Benefit Plan
Issuance of common stock under employee benefit plans, Shares
Leases, Operating [Abstract]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Nature of business and basis of presentation.
Nature Of Business And Basis Of Presentation [Table]
Nature Of Business And Basis Of Presentation [Table]
Consulting services.
Consulting Services [Member]
Consulting Services
Stockholders' Equity, Reverse Stock Split
Reverse stock split
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Nature of the Business and Basis of Presentation
Deferred Revenue
Deferred Revenue, Total
Off-balance sheet risk and concentrations of credit risk.
Off Balance Sheet Risk And Concentrations Of Credit Risk Policy Policy [Text Block]
Off-Balance Sheet Risk and Concentrations of Credit Risk
Sale of Stock [Domain]
Sale of Stock
Liabilities, Current
Total current liabilities
Operating Loss Carryforwards, Total
Operating Loss Carryforwards
Net operating loss carryforwards
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent, Total
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Permanent differences
2024
Lessee, Operating Lease, Liability, to be Paid, Year Three
Loss Contingency Nature [Axis]
Loss Contingency Nature
Operating Leases, Future Minimum Payments Due, Next 12 Months
2023
Fair Value, Recurring [Member]
Recurring
Cash and cash equivalents accumulated gross unrealized losses before tax.
Cash And Cash Equivalents Accumulated Gross Unrealized Losses Before Tax
Cash equivalents, Gross unrealized Losses
Cash equivalents and marketable securities accumulated gross unrealized gains before tax.
Cash Equivalents And Marketable Securities Accumulated Gross Unrealized Loss Before Tax
Total cash equivalents and marketable securities, Gross Unrealized Losses
Income Tax, Policy [Policy Text Block]
Income Taxes
Grants outside of two thousand sixteen stock incentive plan and two thousand nineteen stock incentive plan.
Grants Outside Of Two Thousand Sixteen Stock Incentive Plan And Two Thousand Nineteen Stock Incentive Plan [Member]
Grants Outside of 2016 Stock Incentive Plan and 2019 Stock Incentive Plan
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Treasury Stock, Shares, Ending Balance
Treasury Stock, Shares, Beginning Balance
Treasury Stock, Shares, Total
Treasury Stock, Shares
Treasury stock, shares
Entity Small Business
Entity Small Business
Operating Leased Assets [Line Items]
Deferred tax assets, capitalized research and development costs.
Deferred Tax Assets, Capitalized Research And Development Costs
Capitalized research and development costs
Subsequent to the adoption of ASU 2016-20, as amended member.
Subsequent to the Adoption of ASU 2016-20, as Amended [Member]
Subsequent to the Adoption of ASU 2016-20, as Amended
Research contract costs and accruals.
Research Contract Costs And Accruals Policy [Text Block]
Research Contract Costs and Accruals
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Restructuring and Related Activities [Abstract]
Assets, Current
Total current assets
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
26 Landsdowne Street [Member]
26 Landsdowne Street [Member]
City Area Code
City Area Code
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value, Outstanding
Accounts Receivable, before Allowance for Credit Loss, Current
Accounts receivable
Share-Based Payment Arrangement [Abstract]
Clinical and regulatory milestones payable upon initiation of phase two clinical trial
Clinical And Regulatory Milestones Payable Upon Initiation Of Phase Two Clinical Trial
Specified clinical and regulatory milestones due upon phase two clinical trial
Liabilities
Total liabilities
Private Placement [Member]
Private Placement
Document Period End Date
Document Period End Date
Offering costs
Payments of Stock Issuance Costs
Corporate Bonds
Corporate Bonds [Member]
Corporate bonds.
Restricted Stock [Member]
Restricted Stock
Unvested Restricted Stock Awards
Construction in Progress [Member]
Construction in Process
New Accounting Pronouncements or Change in Accounting Principle [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted average grant date fair value
Lessee, Operating Lease, Renewal Term
Operating lease renewal term
Prepaid research funding payment received.
Prepaid Research Funding Payment Received
Prepaid research funding payment received
Government Agency Securities [Member]
Government Agency Securities [Member]
Government agency securities
Debt Securities, Available-for-Sale, Amortized Cost
Marketable securities, Amortized Cost
Patent cost.
Patent Cost Policy [Text Block]
Patent-Related Costs
Statistical Measurement [Axis]
Statistical Measurement
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Aggregate fair value of securities, unrealized loss position for less than 12 months
Marketable Securities [Table Text Block]
Summary of Marketable Securities
Other Assets, Current
Other
Office and laboratory space
Office and laboratory space
Lease Incentive payable noncurrent.
Lease Incentive Payable Noncurrent
Deferred lease incentive, excluding current portion
Related Party [Axis]
Related Party
Schedule of Restructuring Reserve by Type of Cost [Table Text Block]
Schedule of Restructuring Charges
Assets
Total assets
Accounting Standards Update 2016-02 [Member]
Gross proceeds threshold of automatic conversion of preferred stock to common stock.
Gross Proceeds Threshold Of Automatic Conversion Of Preferred Stock To Common Stock
Gross proceeds threshold of automatic conversion of preferred stock to common stock
Stock Issued During Period, Shares, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock, Shares
State and Local Jurisdiction [Member]
State
Operating Leases, Future Minimum Payments, Due in Four Years
2026
Software Development [Member]
Software
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Proceeds from maturity of marketable securities.
Proceeds From Maturity Of Marketable Securities
Maturities of marketable securities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Antidilutive Securities Excluded from Calculation of Diluted Net Loss per Share Attributable to Common Stockholders
Dividends, Total
Dividends
Dividends declared or paid
Stockholders' Equity, Policy [Policy Text Block]
Fair Value of Common Stock and Series B Convertible Preferred Stock
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Revenue from Contract with Customer, Including Assessed Tax
Collaboration revenue
Document Fiscal Period Focus
Document Fiscal Period Focus
Acquisition Costs, Period Cost
Direct expenses related to the transaction
Increase (Decrease) in Accounts Receivable
Unbilled accounts receivable
Deferred Tax Assets, Valuation Allowance, Total
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued
Preferred stock, $0.001 par value; 5,000,000 shares authorized; no shares issued or outstanding
Other Commitments [Table]
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
Defined Contribution Plan Name
Defined Contribution Plan Name
Defined contribution plan name
Operating Lease, Liability
Total lease liability
Net Cash Provided by (Used in) Financing Activities
Net cash provided by financing activities
Temporary equity stock issued during period shares conversion of convertible securities.
Temporary Equity Stock Issued During Period Shares Conversion Of Convertible Securities
Conversion of convertible preferred stock into common stock, Shares
Issuance of common stock in connection with private placement, net of placement agent fees and offering costs, Shares
Issuance of common stock in connection with private placement, net of placement agent fees and offering costs, Shares
Statement of Financial Position [Abstract]
Temporary Equity, Shares Issued
Convertible preferred stock, share issued
Entity File Number
Securities Act File Number
Series b stock purchase agreement.
Series B Stock Purchase Agreement [Member]
Series B Stock Purchase Agreement
Statement of Cash Flows [Abstract]
Balance Sheet Related Disclosures [Abstract]
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Retirement Benefits [Text Block]
Defined Contribution Plan
Geographical [Domain]
Geographical
Statistical Measurement [Domain]
Statistical Measurement
Statement of Stockholders' Equity [Abstract]
Sale of Stock [Axis]
Sale of Stock
Grants under two thousand nineteen employee stock purchase plan.
Grants Under Two Thousand Nineteen Employee Stock Purchase Plan [Member]
2019 Employee Stock Purchase Plan
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Comprehensive loss:
Auditor Location
Class of Stock [Domain]
Class of Stock
Thereafter
Thereafter
Loss Contingency Accrual, Ending Balance
Loss Contingency Accrual, Beginning Balance
Loss Contingency Accrual
Accrued liabilities for indemnification agreements
Revenue from Contract with Customer [Policy Text Block]
Revenue Recognition
125 Sidney Street [Member]
125 Sidney Street [Member]
Number of directors stockholders are entitled to elect.
Number Of Directors Stockholders Are Entitled To Elect
Number of directors stockholders are entitled to elect
Fair Value Disclosures [Text Block]
Fair Value Measurements
Stock Issued During Period, Shares, Purchase of Assets
Shares issued for asset acquisition
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term (in years), Exercisable
Proceeds from issuance of common stock under benefit plans, net
Proceeds from Issuance of Common Stock
Issuance of Series B convertible preferred stock in connection with asset acquisition, net of issuance costs
Temporary Equity, Stock Issued During Period, Value, New Issues
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Greater than 12 Months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Greater than 12 Months
Debt Securities, Available-for-Sale
Deferred Tax Assets, Tax Credit Carryforwards, Research
Research and development credit carryforwards
Proceeds from sale of marketable securities.
Proceeds From Sale Of Marketable Securities
Sale of marketable securities
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Treasury Stock, Shares, Retired
Retirement of treasury shares
Commitments and contingencies.
Commitments And Contingencies [Table]
Commitments And Contingencies [Table]
Antidilutive Securities [Axis]
Antidilutive Securities
Related Party Transaction, Expenses from Transactions with Related Party
Fees paid in exchange for consulting services
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par value
Milestone Payment for certain Other Identified Targets.
Milestone Payment For Certain Other Identified Targets
Milestone payment for certain other identified targets
Loss Contingency, Nature [Domain]
Loss Contingency, Nature
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Marketable securities, Gross Unrealized Gains
ATM Offering
At-The-Market Offering.
At The Market Offering [Member]
At-The-Market Offering
Supplemental Balance Sheet Disclosures [Text Block]
Additional Balance Sheet Detail
Repayments of Long-Term Capital Lease Obligations
Principal payments on capital lease obligations
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Nature of business and basis of presentation.
Nature Of Business And Basis Of Presentation [Line Items]
Nature Of Business And Basis Of Presentation [Line Items]
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Computer Equipment [Member]
Computer Equipment
General and Administrative Expense [Member]
General and Administrative
Convertible Preferred Stock, Shares Issued upon Conversion
Number of preferred stock converted into common stock
Temporary equity, dividends declared
Temporary Equity Dividends Declared
Temporary equity dividends declared
Commercial Paper [Member]
Commercial Paper
Current Fiscal Year End Date
Current Fiscal Year End Date
Depreciation, Total
Depreciation
Depreciation expense
Financial Instruments [Domain]
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Cash, cash equivalents, and restricted cash, end of period
Cash, cash equivalents, and restricted cash, beginning of period
Stock Repurchased During Period, Shares
Repurchase of unvested restricted stock awards
Other Assets, Noncurrent, Total
Other Assets, Noncurrent
Other assets
Entity Address, Address Line One
Entity Address, Address Line One
Milestone Payment For Certain Identified Targets.
Milestone Payment For Certain Identified Targets
Milestone payment for certain identified targets
Document Annual Report
Document Annual Report
Cash Equivalents and Marketable Securities
Cash, Cash Equivalents, and Marketable Securities [Text Block]
Transaction Type [Axis]
Transaction Type
Represents schedule of prepaid expenses and other current assets.
Schedule Of Prepaid Expenses And Other Current Assets Table [Text Block]
Schedule of Prepaid Expenses and Other Current Assets
Supplemental Cash Flow Information [Abstract]
Supplemental cash flow information
Share Repurchase Program [Domain]
Share Repurchase Program
Percentage of commission on sales price per share
Commission as percentage of sale price per share.
Percentage Of Commission On Gross Sales Price Per Share
Components of Deferred Tax Assets [Abstract]
Deferred tax assets:
Lease Expiration Date
Operating lease end date
Estimated useful life of asset.
Estimated Useful Life Of Asset Table [Text Block]
Schedule of Estimated Useful Life of Asset
Contingent Consideration Type [Domain]
Contingent Consideration Type
Restricted Cash, Noncurrent
Restricted cash
Lessee operating lease written notice period to extend additional lease term.
Lessee Operating Lease Written Notice Period To Extend Additional Lease Term
Written notice period to extend additional lease term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Cancelled
Open Tax Year
Open tax year
Temporary equity stock issued during period value conversion of convertible securities.
Temporary Equity Stock Issued During Period Value Conversion Of Convertible Securities
Conversion of convertible preferred stock into common stock
Income Tax Disclosure [Text Block]
Income Taxes
Preferred Stock, Shares Issued, Total
Preferred Stock, Shares Issued
Preferred stock, shares issued
Payments to Acquire Property, Plant, and Equipment, Total
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Income Tax Disclosure [Abstract]
Capital Lease Obligations, Current
Capital lease obligation, current portion
Commitments and contingencies.
Commitments And Contingencies [Line Items]
Commitments And Contingencies [Line Items]
Increase in common stock capital shares reserved for future issuance.
Increase In Common Stock Capital Shares Reserved For Future Issuance
Increase in number of shares reserved for issuance (shares)
Collaborative Arrangement [Member]
Acceleron Collaboration Agreement
Issuance of common stock, Shares
Stock Issued During Period, Shares, New Issues
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Goodwill and Intangible Assets Disclosure [Abstract]
Number of common stock voting rights.
Number Of Common Stock Voting Rights
Number of common stock voting rights
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Auditor Name
Equity [Abstract]
Schedule of Future Minimum Rental Payments for Operating Leases [Table Text Block]
Schedule of minimum rental commitments
Increase (Decrease) in Accounts and Other Receivables
Accounts receivable
Operating Income (Loss)
Loss from operations
Lessee, Operating Lease, Option to Extend
Operating lease option to extend description
Related Party [Domain]
Related Party
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock
Additional paid-in capital
Temporary Equity, Carrying Amount, Attributable to Parent
Convertible preferred stock, Ending balance
Convertible preferred stock, Beginning balance
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Research and Development in Process
In-process research and development expense
Accrued Professional Fees, Current
Professional services
Common Stock, Voting Rights
Common stock voting rights
Entity Filer Category
Entity Filer Category
Payments to Acquire Marketable Securities, Total
Payments to Acquire Marketable Securities
Purchases of marketable securities
Prepaid expenses.
Prepaid Expenses
Prepaid expenses
Leasehold Improvements, Gross
Operating Expenses
Total operating expenses
Deferred Rent Credit, Noncurrent
Deferred rent, excluding current portion
Entity Current Reporting Status
Entity Current Reporting Status
Stock Issued During Period, Value, Restricted Stock Award, Gross
Vesting of restricted stock awards
Asset Class [Domain]
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate Intrinsic Value, Exercisable
Asset Impairment Charges, Total
Asset Impairment Charges
Impairment losses on long-lived assets
Minimum percentage of shareholders vote or written consent required for automatic conversion.
Minimum Percentage Of Shareholders Vote Or Written Consent Required For Automatic Conversion
Minimum percentage of shareholders vote or written consent required for automatic conversion
Stockholders' Equity Note Disclosure [Text Block]
Common Stock
Stockholders' Equity Attributable to Parent
Ending balance
Beginning balance
Total stockholders’ equity
AOCI Attributable to Parent [Member]
Accumulated other comprehensive loss
Asset Class [Axis]
Asset Class
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location [Axis]
Income Statement Location
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares, Cancelled
Number of Shares, Cancelled
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Common stock, $0.001 par value; 200,000,000 shares authorized; 52,099,211 and 40,636,398 shares issued as of December 31, 2022 and December 31, 2021, respectively; 52,099,211 and 40,626,224 shares outstanding as of December 31, 2022 and December 31, 2021, respectively
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Equity Components [Axis]
Equity Components
Tax credit carryforward expiration year.
Tax Credit Carryforward Expiration Year
Tax credit carryforwards, Expiration year
Income taxes disclosure.
Income Taxes Disclosure [Line Items]
Income Taxes Disclosure [Line Items]
Accounting Standards Update [Domain]
Range of tiered royalties on net sales.
Range Of Tiered Royalties On Net Sales
Range of tiered royalties on net sales
Lab equipment.
Lab Equipment [Member]
Lab Equipment
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Other than Temporary Impairment Losses, Investments, Total
Other than Temporary Impairment Losses, Investments
Securities with other-than-temporary impairment
Leases [Abstract]
Unrecognized Tax Benefits, Income Tax Penalties Accrued
Accrued penalties related to uncertain tax positions
Entity Emerging Growth Company
Entity Emerging Growth Company
Related Party Transaction [Axis]
Related Party Transaction
Operating Expenses [Abstract]
Operating expenses:
Third Rock Ventures LLC.
Third Rock Ventures L L C [Member]
TRV
Stock Issued During Period, Value, Purchase of Assets
Shares issued for asset acquisition, estimated fair value
Schedule of Stock by Class [Table]
Schedule Of Stock By Class [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (years)
Transaction [Domain]
Transaction
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Voluntary Filers
Entity Voluntary Filers
Cumulative catch-up adjustment
Cumulative Catch Up Adjustment
Cumulative Catch-Up Adjustment
Research Tax Credit Carryforward [Member]
Research and Development
Schedule of Research and Development Assets Acquired Other than Through Business Combination [Table]
Schedule Of Research And Development Assets Acquired Other Than Through Business Combination [Table]
Retirement Benefits [Abstract]
Document Transition Report
Document Transition Report
Operating Leases, Rent Expense, Total
Operating Leases, Rent Expense
Rent expense
Operating Loss Carryforwards, Valuation Allowance, Total
Operating Loss Carryforwards, Valuation Allowance
Increase in valuation allowance
Assets, Fair Value Disclosure
Total
Assets, Fair Value Disclosure, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Granted
Collaborative Arrangement Disclosure [Text Block]
Collaboration and License Agreements
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Amendment Description
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Exercised
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive loss
Marketable Securities, Policy [Policy Text Block]
Marketable Securities
Accrued liabilities and other current liabilities.
Accrued Liabilities And Other Current Liabilities
Accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Other Comprehensive Income (Loss), Net of Tax
Total other comprehensive loss
Accounting Standards Update and Change in Accounting Principle [Table Text Block]
Schedule of Accounting Standards Update and Change in Accounting Principle
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Cash and cash equivalents amortized cost.
Cash And Cash Equivalents Amortized Cost
Cash equivalents, Amortized Cost
Income taxes disclosure.
Income Taxes Disclosure [Table]
Income Taxes Disclosure [Table]
GSK agreement.
G S K Agreement [Member]
GSK Agreement
Operating Lease, Liability, Current
Operating lease liability, current
Additional Paid-in Capital [Member]
Additional Paid-In Capital
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Deferred Tax Assets, Operating Loss Carryforwards, Total
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Weighted Average Remaining Contractual Term (in years), Outstanding, Beginning Balance
Weighted Average Remaining Contractual Term (in years), Outstanding, Beginning Balance
Entity Registrant Name
Entity Registrant Name
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Earnings Per Share [Text Block]
Net Loss per Share
Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Weighted Average Assumptions Used to Calculate Fair Value of Stock Option
Class of Stock [Axis]
Class of Stock
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Property, Plant and Equipment, Net, Ending Balance
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Recently adopted accounting pronouncements.
Recently Adopted Accounting Pronouncements Policy [Text Block]
Recently Adopted Accounting Pronouncements
Award Type [Domain]
Award Type
Statement [Line Items]
Statement [Line Items]
Operating Lease, Expense
Temporary Equity, by Class of Stock [Table]
Temporary Equity By Class Of Stock [Table]
Shares reserved for conversion of preferred stock and future issuance of common stock.
Shares Reserved For Conversion Of Preferred Stock And Future Issuance Of Common Stock
Shares reserved for conversion of preferred stock and future issuance of common stock
Title of 12(b) Security
Title of 12(b) Security
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Common Stock [Member]
Common Stock
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Net Cash Provided by (Used in) Operating Activities [Abstract]
Operating activities
Leaseholds and Leasehold Improvements [Member]
Capital Leases
Equity Component [Domain]
Equity Component
Convertible Preferred Stock [Member]
Convertible Preferred Stock
Revenue from Contract with Customer, Excluding Assessed Tax, Total
Revenue from Contract with Customer, Excluding Assessed Tax
Revenues
Area of properties held under operating leases.
Area Of Properties Held Under Operating Leases
Square feet of office and laboratory space leased under operating lease
Entity Address, State or Province
Entity Address, State or Province
2025
Lessee, Operating Lease, Liability, to be Paid, Year Four
Geographical [Axis]
Geographical
Net decrease in cash, cash equivalents and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Document Type
Document Type
Accrued research and development expenses.
Accrued Research And Development Expenses
External research and development
Share Repurchase Program [Axis]
Share Repurchase Program
Entity Shell Company
Entity Shell Company
2022 Inducement Stock Incentive Plan
TwoThousandTwentyTwoInducementStockIncentivePlan [Member]
TwoThousandTwentyTwoInducementStockIncentivePlan [Member]
Fair Value of Financial Instruments, Policy [Policy Text Block]
Fair Value of Financial Instruments
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Accrued Liabilities
Accrued expenses and other
Prior to the adoption of ASU 2016, as amended member.
Prior to the Adoption of ASU 2016, as Amended [Member]
Prior to the Adoption of ASU 2016, as Amended
Series A convertible preferred stock.
Series A Convertible Preferred Stock [Member]
Series A Convertible Preferred Stock
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Corporate Bond Securities [Member]
Corporate Bonds
Unrecognized Tax Benefits, Interest on Income Taxes Accrued
Accrued interest related to uncertain tax positions
Security Exchange Name
Security Exchange Name
Class of Stock [Line Items]
Class Of Stock [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation expense, weighted average period expect to recognized
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted Average Remaining Contractual Term (in years), Outstanding
Contractual term
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Other comprehensive loss:
Commitments and Contingencies Disclosure [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Schedule of Future Minimum Lease Payments
Right of Reference and License Agreement
The entire disclosure for asset acquisition.
Asset Acquisition Disclosure [Text Block]
Consolidation, Policy [Policy Text Block]
Principles of Consolidation
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of Restricted Stock Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements-To Be Adopted
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding
Common stock, shares outstanding
Accretion (Amortization) of Discounts and Premiums, Investments
Net amortization of premiums and discounts on marketable securities
Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent
Federal and state research and development credits
Fair Value, Inputs, Level 2 [Member]
Level 2
Deferred Revenue, Current, Total
Deferred Revenue, Current
Deferred revenue, current portion
Debt Securities, Available-for-sale, Total
Debt Securities, Available-for-Sale
Marketable securities
Marketable securities, Fair Value
Net Cash Provided by (Used in) Investing Activities [Abstract]
Investing activities
Commitments and Contingencies
Commitments and contingencies (Note 12)
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, shares issued
Due to Related Parties, Current, Total
Due to Related Parties, Current
Due to related party
US Treasury Securities [Member]
U S Treasury Securities [Member]
Non-refundable upfront payments received.
Non Refundable Upfront Payments Received
Non refundable upfront payment received
Minimum [Member]
Minimum [Member]
Marketable Securities, Total
Marketable Securities
Marketable securities
Less: imputed interest
Less: imputed interest
Operating Leases, Rent Expense, Net [Abstract]
Lessee, Leases [Policy Text Block]
Leases
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted Average Exercise Price, Exercisable
Accounting Standards Update [Axis]
Lessor, Operating Lease, Term of Contract
Tax Credit Carryforward [Axis]
Tax Credit Carryforward
Member stands for legal proceedings.
Legal Proceedings [Member]
Legal Proceedings
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders’ equity:
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State income tax, net of federal benefit
Issuance of Series B convertible preferred stock in connection with asset acquisition, net of issuance costs, Shares
Temporary equity, stock issued during period, shares, new issues.
Temporary Equity Stock Issued During Period Shares New Issues
Variable Lease, Payment
Schedule of Stock by Class [Table Text Block]
Schedule of Potential Conversion of Preferred Stock and Future Issuance of Common Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value, Cancelled
Cash equivalents and marketable securities fair value disclosure.
Cash Equivalents And Marketable Securities Fair Value Disclosure
Total cash equivalents and marketable securities, Fair Value
Award Type [Axis]
Award Type
Subsequent Event [Member]
Subsequent Event
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation expense
Related Party Transaction [Domain]
Related Party Transaction
Deferred Tax Assets, Gross
Gross deferred tax assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Impairment of Long-Lived Assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Total intrinsic value of stock options exercised
Share based compensation arrangement by share based payment award equity instruments other than options repurchased in period.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Repurchased In Period
Number of Shares, Repurchased
Proceeds from issuance of common stock in connection with private placement, net of placement agent fees and offering costs
Net proceeds of after deducting offering costs
Proceeds from Issuance of Private Placement
Specified clinical and regulatory milestones phase two clinical trial
Clinical And Regulatory Milestone Payables Upon Phase Two Clinical Trial
Clinical and regulatory milestone payables upon phase two clinical trial.
Research and Development Expense, Total
Research and Development Expense
Research and development
Lessee, Operating Lease, Liability, to be Paid
Total commitment
Total minimum lease payments
Lessee, Operating Lease, Term of Contract
Operating lease term
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments
Expected dividend yield
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Entity Central Index Key
Entity Central Index Key
Operating Leases, Future Minimum Payments, Due in Two Years
2024
Preferred Stock [Text Block]
Preferred Stock
Accounting Policies [Abstract]
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Accrued expenses and other liabilities
Investments, Debt and Equity Securities [Abstract]
Debt Securities, Available-for-Sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Weighted Average Remaining Contractual Term (in years), Outstanding, Ending balance
Weighted Average Remaining Contractual Term (in years), Outstanding, Ending balance
Interest Receivable
Interest income receivable
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Accumulated depreciation
Less: accumulated depreciation
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected stock price volatility
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Abstract]
Clinical and regulatory milestones due upon initiation of phase two clinical trial recorded as expense.
Clinical And Regulatory Milestones Due Upon Initiation Of Phase Two Clinical Trial Recorded As Expense
Clinical and regulatory milestones due upon phase two clinical trial recorded as expense
Other Commitments [Domain]
Other Commitments
Measurement Frequency [Axis]
Measurement Frequency
Share-Based Payment Arrangement [Text Block]
Stock-based Compensation Expense
Effective income tax rate reconciliation, ownership change, percent.
Effective Income Tax Rate Reconciliation, Ownership Change, Percent
Impact of ownership change
Aggregate Restructuring Charges
Aggregate Restructuring Charges
Aggregate Restructuring Charges
General and Administrative Expense, Total
General and Administrative Expense
General and administrative
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Exercise Price, Outstanding, Ending balance
Weighted Average Exercise Price, Outstanding, Beginning balance
Loss Contingency, Loss in Period
Expenses incurred for legal proceedings
Research and Development Expense [Member]
Research and Development
Public Utilities, Inventory [Table]
Public Utilities Inventory [Table]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Retained Earnings [Member]
Accumulated Deficit
Security Deposit
Clinical and regulatory milestone due upon initiation of phase two clinical trial achieved and paid.
Clinical And Regulatory Milestone Due Upon Initiation Of Phase Two Clinical Trial Achieved And Paid
Clinical and regulatory milestone due upon phase two clinical trial achieved and paid
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name
Money Market Funds [Member]
Money Market Funds
Effective Income Tax Rate Reconciliation, Percent
Effective income tax rate
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross
Total property and equipment
Total property and equipment, gross
Worldwide net sales milestones.
Worldwide Net Sales Milestones [Member]
Worldwide Net Sales Milestones
Minimum percentage of outstanding shares of preferred stock for liquidation preference.
Minimum Percentage Of Outstanding Shares Of Preferred Stock For Liquidation Preference
Minimum percentage of outstanding shares of preferred stock for liquidation preference
Entity Interactive Data Current
Entity Interactive Data Current
Tax Credit Carryforward, Amount
Tax credit carryforwards
Amount of minimum lease payments for capital leases due after the second fiscal year, December 31, 2021.
Capital Leases Future Minimum Payments Due After Year Two
Future minimum lease payments, after 2021
Entity Public Float
Entity Public Float
Increase Decrease In Operating Lease Assets And Liabilities
Increase Decrease In Operating Lease Assets And Liabilities
Operating lease assets and liabilities
Operating lease assets and liabilities
Related Party Transactions Disclosure [Text Block]
Related-Party Transactions
Letters of Credit Outstanding, Amount
Letters of credit
Temporary Equity [Line Items]
Temporary Equity [Line Items]
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Non-cash investing and financing activities:
Related Party Transactions [Abstract]
2022
Lessee, Operating Lease, Liability, to be Paid, Year One
Cash paid for operating lease liabilities
Cash paid for operating lease liabilities
Cash paid for operating lease liabilities
Leasehold Improvements [Member]
Leasehold Improvements
Temporary Equity, Shares Outstanding
Convertible preferred stock, Ending balance, Shares
Convertible preferred stock, Beginning balance, Shares
Convertible preferred stock, share outstanding
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Aggregate fair value of securities, unrealized loss position for more than 12 months
Net proceeds of common stock
Proceeds from initial public offering of common stock, net of underwriting discounts and commissions
Proceeds from Issuance Initial Public Offering
Local Phone Number
Local Phone Number
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Federal income tax at statutory rate
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets Measured at Fair Value on Recurring Basis and Level of Fair Value Hierarchy Utilized
Two thousand sixteen stock incentive plan.
Two Thousand Sixteen Stock Incentive Plan [Member]
2016 Stock Incentive Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Capital Leases, Future Minimum Payments Due in Two Years
Future minimum lease payments, 2021
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Public Utilities, Inventory [Line Items]
Public Utilities Inventory [Line Items]
Capital Leases, Future Minimum Payments Due, Next 12 Months
Future minimum lease payments, 2020
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Number of Shares, Exercisable
IPO [Member]
IPO
Lessee, Operating Lease, Existence of Option to Extend [true false]
Operating lease option to extend
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of Shares, Granted
Upfront payment.
Upfront Payment
Upfront payment
Accounting Standards Update 2016-02 Cumulative Effect, Period of Adoption [Member]
Effect of Adoption
Other Liabilities, Noncurrent, Total
Other Liabilities, Noncurrent
Other liabilities, excluding current portion
Income Statement Location [Domain]
Income Statement Location
Operating loss carryforwards indefinitely.
Operating Loss Carryforwards Indefinitely
Net operating loss carryforwards indefinitely
Property, Plant and Equipment [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of Shares, Unvested, Ending balance
Number of Shares, Unvested, Beginning balance
Shares, Outstanding
Ending balance, Shares
Beginning balance, Shares
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Contingent Consideration by Type [Axis]
Contingent Consideration by Type
Grants under two thousand nineteen stock incentive plan.
Grants Under Two Thousand Nineteen Stock Incentive Plan [Member]
2019 Stock Incentive Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Shares, Outstanding, Ending balance
Number of Shares, Outstanding, Beginning balance
Marketable Securities, Current, Total
Marketable Securities, Current
Marketable securities
Document Fiscal Year Focus
Document Fiscal Year Focus
Workforce reduction
Workforce reduction
Workforce reduction
2023
Lessee, Operating Lease, Liability, to be Paid, Year Two
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Indemnification Agreement [Member]
Indemnification Agreement
Assets [Abstract]
Assets
Deferred Tax Assets, Net
Net deferred tax assets
Prepaid Expense and Other Assets, Current
Prepaid expenses and other current assets
Total prepaid expenses and other current assets
Emerging growth company policy.
Emerging Growth Company Policy Policy [Text Block]
Emerging Growth Company Status
Preferred stock conversion price per share.
Preferred Stock Conversion Price Per Share
Preferred stock conversion price per share
Treasury Stock, Value, Ending Balance
Treasury Stock, Value, Beginning Balance
Treasury Stock, Value, Total
Treasury Stock, Value
Treasury stock, at cost; no shares as of December 31, 2020 and December 31, 2019
Treasury stock, at cost; no shares
Share price
Shares Issued, Price Per Share
Shares issued, price per share
Interest Income (Expense), Nonoperating, Net
Other income, net
Series A Preferred Stock [Member]
Series A Preferred Stock
Financial Instrument [Axis]
Series B convertible preferred stock.
Series B Convertible Preferred Stock [Member]
Series B Convertible Preferred Stock
Unbilled accounts receivable related to reimbursable research and development cost.
Unbilled Accounts Receivable Related To Reimbursable Research And Development Cost
Unbilled Accounts Receivable Related To Reimbursable Research And Development Cost
Accrued Restructuring Charges
Accrued Restructuring Charges
Accrued restructuring charges Beginning
Accrued restructuring charges Ending
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Deferred Tax Assets, Deferred Income
Deferred revenue
Schedule of Operating Leased Assets [Table]
Research and Development Assets Acquired Other than Through Business Combination [Line Items]
Research And Development Assets Acquired Other Than Through Business Combination [Line Items]
Liabilities and Equity [Abstract]
Liabilities and stockholders’ equity
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Deferred Rent
Deferred rent
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment
Research, development and sales arrangement aggregate amount receivable upon achievement of milestone.
Research Development And Sales Arrangement Aggregate Amount Receivable Upon Achievement Of Milestone
Aggregate amount receivable on achievement of milestone
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Income Tax Authority [Axis]
Income Tax Authority
Deferred Tax Assets, Net of Valuation Allowance
Net deferred tax assets
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Temporary Equity Disclosure [Abstract]
Assets, Current [Abstract]
Current assets:
Dividends, Common Stock, Total
Dividends, Common Stock
Common stock dividends declared
Stock issued during period value Initial public offering net of underwriting discounts, commissions and offering costs.
Stock Issued During Period Value Initial Public Offering Net Of Underwriting Discounts Commissions And Offering Costs
Initial public offering, net of underwriting discounts, commissions and offering costs
MASSACHUSETTS
Cambridge, Massachusetts
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Deferred Tax Assets and Liabilities
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Defined Contribution Plan, Employer Discretionary Contribution Amount
Employer Discretionary Contribution Amount
Lessor, Operating Lease, Renewal Term
Measurement Frequency [Domain]
Measurement Frequency
Accrued restricted stock liability, current.
Accrued Restricted Stock Liability Current
Restricted stock liability, current portion
Fair value transfers between levels.
Fair Value Transfers Between Levels
Fair value transfers between levels
Payments for Operating Activities, Total
Payments for Operating Activities
Amounts paid during the period
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Operating Leases, Future Minimum Payments, Due in Three Years
2025
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
Effective income tax rate reconciliation federal orphan drug credits.
Effective Income Tax Rate Reconciliation Federal Orphan Drug Credits
Federal orphan drug credits
Cash equivalents and marketable securities amortized cost basis.
Cash Equivalents And Marketable Securities Amortized Cost Basis
Total cash equivalents and marketable securities, Amortized Cost
Restructuring and Related Activities Disclosure [Text Block]
Restructuring Activities
Lessee, Operating Lease, Remaining Lease Term
MyoKardia Collaboration Agreement.
Myo Kardia Collaboration Agreement [Member]
MyoKardia Collaboration and License Agreement
Cover [Abstract]
The cash inflow associated with the amount received from entity's secondary offering of stock to the public.
Proceeds from Issuance of Common Stock in Connection with Follow-on Offering
Proceeds from issuance of common stock in connection with public offerings, net of issuance costs
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense, Total
Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense
Penalties and interest expense related to income taxes
2026
Lessee, Operating Lease, Liability, to be Paid, Year Five
Clinical and regulatory milestones.
Clinical And Regulatory Milestones [Member]
Clinical and Regulatory Milestones
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of Shares, Vested
Clinical and regulatory milestone payables.
Clinical And Regulatory Milestone Payables
Specified clinical and regulatory milestones
ASC 840 member.
ASC 840 [Member]
Liabilities, Current [Abstract]
Current liabilities:
Maximum [Member]
Maximum
Two thousand nineteen stock incentive plan.
Two Thousand Nineteen Stock Incentive Plan [Member]
2019 Stock Incentive Plan
Deferred tax assets lease incentive.
Deferred Tax Assets Lease Incentive
Deferred lease incentive
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Unrealized loss on marketable securities
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Stock-Based Compensation Expense Recognized
Net Cash Provided by (Used in) Investing Activities
Net cash used in investing activities
Furniture and Fixtures [Member]
Furniture and Fixtures
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Prepaid sign-on bonuses subject to vesting provisions.
Prepaid Sign On Bonuses Subject To Vesting Provisions
Prepaid sign-on bonuses subject to vesting provisions
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Number of Shares, Exercised
Operating Leases, Future Minimum Payments Due, Fiscal Year Maturity [Abstract]
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Stock Issued During Period, Shares, Restricted Stock Award, Gross
Vesting of restricted stock awards, Shares
Shares reserved for vesting of restricted stock units
Deferred Tax Liabilities, Gross, Total
Deferred Tax Liabilities, Gross
Deferred tax liability
Stock Issued During Period, Shares, Issued for Services
Common stock shares issued in exchange for services
Member stands for commitment for office and laboratory space lease of current corporate headquarters.
Commitment For Office And Laboratory Space Lease Of Current Corporate Headquarters [Member]
Commitment for Office and Laboratory Space Lease of Current Corporate Headquarters
Segment Reporting, Policy [Policy Text Block]
Segment Information
Accounts and Financing Receivable, after Allowance for Credit Loss, Total
Accounts and Financing Receivable, after Allowance for Credit Loss
Accounts and Financing Receivable, after Allowance for Credit Loss
Property, Plant and Equipment, Useful Life
Estimated useful life of asset
Sales milestone.
Sales Milestone
Specified sales milestone
Preferred Stock, Dividend Rate, Per-Dollar-Amount
Preferred stock, dividend per share
Preferred Stock, Convertible, Terms
Convertible preferred stock, terms of conversion
Common Stock, Shares Authorized
Common stock, shares authorized
Trading Symbol
Trading Symbol
Other Commitments [Line Items]
Subsequent Event Type [Axis]
Subsequent Event Type
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Percent, Total
Effective Income Tax Rate Reconciliation, Other Reconciling Items, Percent
Other
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Comprehensive loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Accounts Payable, Current, Total
Accounts Payable, Current
Accounts payable
Operating loss carryforwards expiration year.
Operating Loss Carryforwards Expiration Year
Net operating loss carryforwards expiration beginning year
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Marketable securities, Gross Unrealized Losses
Increase (Decrease) in Other Operating Assets, Total
Increase (Decrease) in Other Operating Assets
Other assets
Plan Name [Axis]
Plan Name
Schedule of Related Party Transactions, by Related Party [Table]
Schedule Of Related Party Transactions By Related Party [Table]
Research milestone.
Research Milestone [Member]
Research Milestones
Aggregate fair value of securities, Remaining contractual maturity of greater than one year
Aggregate fair value of securities, Remaining contractual maturity of greater than one year
Aggregate fair value of securities
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Restructuring and Related Cost, Incurred Cost
Restructuring expenses
Common Stock, Par or Stated Value Per Share
Common stock, par value
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Stock Issued During Period, Value, Conversion of Convertible Securities
Conversion of convertible preferred stock into common stock
Comprehensive Income, Policy [Policy Text Block]
Comprehensive Loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of Shares, Granted
Property, Plant and Equipment Disclosure [Text Block]
Property and Equipment, Net
Property, Plant and Equipment, Estimated Useful Lives
Leasehold improvements
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted Average Exercise Price, Granted
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Antidilutive securities excluded from calculation of diluted net loss per share
Cash and Cash Equivalents, Fair Value Disclosure
Cash equivalents
Cash equivalents, Fair Value