SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person* Tourangeau Greg (Last) (First) (Middle) C/O FULCRUM THERAPEUTICS, INC. 26 LANDSDOWNE STREET (Street) CAMBRIDGE MA 02139 (City) (State) (Zip)	2. Date of Event Requiring Statement (Month/Day/Year) 03/11/2022	3. Issuer Name and Ticker or Trading Symbol Fulcrum Therapeutics, Inc. [ FULC ]
		4. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director 10% Owner X Officer (give title below) Other (specify below) Controller	5. If Amendment, Date of Original Filed (Month/Day/Year)
			6. Individual or Joint/Group Filing (Check Applicable Line) X Form filed by One Reporting Person Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	12,952	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Stock Option (right to buy)	(1)	01/21/2029	Common Stock	685	7.84	D
Stock Option (right to buy)	(2)	05/20/2029	Common Stock	1,339	11.06	D
Stock Option (right to buy)	(3)	07/17/2029	Common Stock	374	16	D
Stock Option (right to buy)	(4)	01/22/2030	Common Stock	3,410	16.87	D
Stock Option (right to buy)	(5)	01/24/2031	Common Stock	7,278	13.09	D
Stock Option (right to buy)	(6)	01/25/2032	Common Stock	9,868	12.46	D

Explanation of Responses:

1. The reporting person received an option to purchase a total of 2,192 shares on January 22, 2019. 1,507 shares underlying the option were previously exercised by the reporting person. The shares underlying the option are scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of January 1, 2019, subject to continued service.

2. The reporting person received an option to purchase a total of 3,571 shares on May 21, 2019. 2,232 shares underlying the option were previously exercised by the reporting person. The shares underlying the option are scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of May 15, 2019, subject to continued service.

3. This option was granted on July 18, 2019 and is scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of July 1, 2019, subject to continued service.

4. This option was granted on January 23, 2020 and is scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of January 1, 2020, subject to continued service.

5. This option was granted on January 25, 2021 and is scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of January 1, 2021, subject to continued service.

6. This option was granted on January 26, 2022 and is scheduled to vest in equal quarterly installments over four years beginning on the vesting commencement date of January 1, 2022, subject to continued service.

Remarks:

	/s/ Gregory Tourangeau	03/14/2022
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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